Dry goods | Plant metabolomics case sharing

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【Summary description】In 2011, a drought resistance study led by Dr. Melvin J. Oliver of the United States Department of Agriculture and Dr. Lining Guo of the former Metabolon Company was published in the journal Plant Cell, using metabolomics methods to conduct an in-depth discussion on the drought resistance mechanism of herbs ( Oliver, M. J., et al. A sister group contrast using untargetedglobal metabolomic analysis delineates the biochemical regulation underlyingdesiccation tolerance in Sporobolus stapfianus. Plant Cell, 2011. 23(4):1231-48). The two drought-resistant phenotypes they used were Sporobolus stapfianus and Sporobolus pyramidalis, two different species of the same genus Salina. Although the two are plants of the same genus, they have markedly different responses to drought. Among them, S. pyramidalis is sensitive to drought, while S. stapfianus is highly drought-resistant. Drought-sensitive S. pyramidalis began to die when the relative water content (RWC) was less than 60% after the onset of drought. In contrast, drought-resistant S. stapfianus survived with RWCs as low as 5% after the onset of drought.

In 2011, a drought resistance study led by Dr. Melvin J. Oliver of the United States Department of Agriculture and Dr. Lining Guo of the former Metabolon Company was published in the journal Plant Cell, using metabolomics methods to conduct an in-depth discussion on the drought resistance mechanism of herbs ( Oliver, M. J., et al. A sister group contrast using untargetedglobal metabolomic analysis delineates the biochemical regulation underlyingdesiccation tolerance in Sporobolus stapfianus. Plant Cell, 2011. 23(4):1231-48).
The two drought-resistant phenotypes they used were Sporobolus stapfianus and Sporobolus pyramidalis, two different species of the same genus Salina. Although the two are plants of the same genus, they have markedly different responses to drought. Among them, S. pyramidalis is sensitive to drought, while S. stapfianus is highly drought-resistant. Drought-sensitive S. pyramidalis began to die when the relative water content (RWC) was less than 60% after the onset of drought. In contrast, drought-resistant S. stapfianus survived with RWCs as low as 5% after the onset of drought.

Monkeypox virus nucleic acid detection kit obtained EU CE certification

Prevention of monkeypox virus: avoid contact with animals that may carry monkeypox virus (primates, rodents, marsupials in southern Africa); avoid eating game, especially when traveling in southern Africa; Items that sick animals have been in contact with, such as bedding; isolate infected patients from other people who may be at risk of infection; practice good hand hygiene, such as washing hands with soap and water, after contact with infected animals or humans , or use alcohol-based hand sanitizer; use personal protective equipment (PPE) when caring for monkeypox patients; vaccination against monkeypox is 85% effective.

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Gene preservation helps run precision medicine

"Healthy Dream" is an important part of "Chinese Dream". On November 21, 2015, Zhan Qimin, academician of the Chinese Academy of Engineering, vice president of the Chinese Academy of Medical Sciences, and vice president of the China Union Medical University, made a speech at the "From Gene Sequencing to Precision Medicine Development Strategy Seminar and the 134th Zhejiang University West Lake Forum". The theme report of "Strategic Requirements and Key Tasks for the Development of Precision Medicine" discusses the strategic needs and key tasks for the development of precision medicine in my country. In particular, the "health dream" is an important part of the "Chinese dream", and environmental factors can cause genetic changes (gene mutation, etc.), which leads to the occurrence of various major diseases (such as smoking and tumors). Gene mutations are individual differences, taking breast tumors as an example, P53 mutation, BRCA1 mutation, Ras mutation, Wnt mutation, EGFR mutation, etc. All of them may suffer from breast cancer, so different people's genotypes need to be considered when clinical medication is used, which may have different drug effects on the same drug. Academician Zhan finally put forward several ideas for tumor precision medicine, including the establishment of a biological sample bank; Build a gene and protein analysis platform; build a big data platform.

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WHO updates guidelines, HPV screening will usher in new changes

On July 6, 2021, the World Health Organization (WHO) and the United Nations Special Programme on Human Reproduction (HRP) released the second edition of the Guidelines for the Screening and Treatment of Cervical Precancers. The guidelines aim to update existing WHO recommendations on cervical cancer prevention screening and treatment, helping countries make faster and more equitable progress in cervical cancer screening and treatment. Currently commonly used cervical cancer screening methods include: cytology, visual inspection with acetic acid (VIA), and HPV DNA testing. In this guideline update, HPV-DNA-based testing is particularly recommended as the preferred method for cervical cancer screening. The advantages of HPV-DNA testing are:

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